Hibernating myocardium: clinical and functional response to revascularisation
نویسندگان
چکیده
منابع مشابه
Hibernating myocardium.
Decreased myocardial contraction occurs as a consequence of a reduction in blood flow. The concept of hibernation implies a downregulation of contractile function as an adaptation to a reduction in myocardial blood flow that serves to maintain myocardial integrity and viability during persistent ischemia. Unequivocal evidence for this concept exists in scenarios of myocardial ischemia that last...
متن کاملEVects of coronary revascularisation on myocardial blood flow and coronary vasodilator reserve in hibernating myocardium
Objective—Previous studies have suggested that resting myocardial blood flow is within normal limits in most chronically dysfunctional left ventricular segments which improve function after coronary artery revascularisation (hibernating myocardium). The aim of this study was to assess myocardial blood flow and coronary vasodilator reserve in hibernating myocardium before and after coronary reva...
متن کاملEffects of coronary revascularisation on myocardial blood flow and coronary vasodilator reserve in hibernating myocardium.
OBJECTIVE Previous studies have suggested that resting myocardial blood flow is within normal limits in most chronically dysfunctional left ventricular segments which improve function after coronary artery revascularisation (hibernating myocardium). The aim of this study was to assess myocardial blood flow and coronary vasodilator reserve in hibernating myocardium before and after coronary reva...
متن کاملREVIEW IN DEPTH Clinical pathophysiology of hibernating myocardium
Our current knowledge of the pathophysiology of chronic hibernating myocardium is mainly based on results from clinical studies, because of the absence of appropriate and validated animal models. These clinical observations have given rise to two major controversies: the role of reduced blood flow and that of histological changes in the hibernating segments. In this review, these two subjects w...
متن کاملThe Sleeping Heart : Hibernating Myocardium
Classical teaching about myocardial ischemia is now being challenged by exciting new concepts that have been evolving over the past two decades. It is now recognized that prolonged myocardial ischemia does not inevitably lead to irreversible necrosis of myocardial tissue. Similarly, segment dysfunction in the ventricle does not necessarily imply that the myocardium in that area has undergone in...
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ژورنال
عنوان ژورنال: European Journal of Cardio-Thoracic Surgery
سال: 1997
ISSN: 1010-7940
DOI: 10.1016/s1010-7940(97)01211-6